目的：评估黄斑色素光学密度(MPOD)、中央黄斑厚度与体重指数(BMI)的关系。

方法：这是一项在单一机构中进行比较的横断面研究。本研究共纳入210名符合入选标准的志愿者。使用黄斑色素筛选剂II对受试者MPOD进行测量。使用SD Cirrus OCT测量中央黄斑厚度。记录所有眼MPOD和OCT信息。使用Microsoft^©；Excel，SPSS和R进行数据分析。

结果：MPOD和中央黄斑厚度之间呈明显正相关(r=0.42， P<0.01)。同时，MPOD和BMI之间呈明显负相关(r=-0.23， P<0.01)。

结论：研究得出，MPOD和中央黄斑厚度之间呈明显正相关。还需要进一步研究中央凹的详细结构及其与MPOD的关系。研究发现了MPOD与BMI之间呈明显正相关，且得出BMI的降低可能会增加黄斑色素的密度，这有助于预防年龄相关性黄斑变性(ARMD)。

METHODS: This is a comparative cross-sectional study performed in a single institution. Totally 210 volunteers who met the inclusion criteria were included in this study. The subject's MPOD was measured using Macula Pigment Screener II(MPS II, by Electron Technology). Central macular thickness was measured with Spectral Domain Cirrus Optical Coherence Tomography(OCT), Cirrus(Model 4000, Carl Zeiss Meditec). The information of both MPOD and OCT from both eyes were recorded. The data was analysed using Microsoft^© Excel \〖Version 15.12.3(150724)℃2015 Microsoft\〗, SPSS(IBM^© SPSS^© Statistics Version 2.2), and R(version 3.2.1; R Core Team 2015).

RESULTS: There was significant positive correlation between MPOD and central macular thickness(r=0.42, P<0.01)and a significant negative correlation between MPOD and BMI(r=-0.23, P<0.01).

CONCLUSION: Our study showed a significant positive correlation between MPOD and central macular thickness. Further study is needed to look at the detailed structure of the fovea and its relationship with MPOD. Our study also found a significant negative correlation between MPOD and BMI, suggesting that a reduction in BMI may increase the density of macula pigment, which can be helpful in preventing age-retinal pigment epitheliitis(ARMD).