目的：分析睑板腺功能障碍患者睫毛蠕形螨感染的临床特征。

方法：回顾性研究。选取2016-11/2018-06就诊于本院的睑板腺功能障碍患者220例440眼，根据是否并发睫毛蠕形螨感染将其分为未感染组和感染组，每组110例220眼，检测对比两组患者各项眼部功能指标，评估睫毛蠕形螨感染的临床特点。

结果：感染组患者瘙痒感、异物感、眼痛、干涩感等临床症状发生率明显高于非感染组(P<0.05)，眼红、分泌物增多、疲劳感、畏光等症状发生率无明显差异(P>0.05)； 两组平均泪膜破裂时间、基础泪液分泌量均明显低于正常水平，且感染组低于非感染组(P<0.05)； 非感染组角膜染色评分及睑板腺分泌功能评分均低于感染组(P<0.05)。

结论：睑板腺功能障碍患者发生睫毛蠕形螨感染后更容易出现瘙痒、干涩、眼痛等症状，增加角结膜上皮损害，重视蠕形螨感染检查对睑板腺功能障碍患者意义重大。

METHODS: A retrospective study. Totally 220 patients(440 eyes)with meibomian gland dysfunction were selected from November 2016 to June 2018. They were divided into uninfected group and infected group according to the concurrence of eyelash demodex infection. 110 patients(220 eyes)in each group. The ocular function indexes of the two groups were tested and compared, and the clinical characteristics of eyelash demodex infection were evaluated.

RESULTS: The incidence of itching, foreign body sensation, eye pain, dryness and astringency in the infected group was significantly higher than that in the non-infected group(P<0.05), and there was no significant difference in the incidence of symptoms such as redness, secretion increase, fatigue and photophobia(P>0.05); the average tear film rupture time and basic tear secretion in the two groups were significantly lower than that in the normal level, and the infected group was significantly lower than that in the non-infected group(P<0.05). Corneal staining score and tarsal gland secretion function score in non-infected group were significantly lower than those in infected group(P<0.05).

CONCLUSION: Patients with tarsal gland dysfunction are more likely to suffer from itching, dryness, eye pain and other symptoms after eyelash demodex infection, which increases the damage of corneal and conjunctival epithelium. It is of great significance to pay attention to demodex infection examination for patients with tarsal gland dysfunction.