目的：观察智能脉冲技术(SPT)辅助的经上皮准分子激光角膜切削术(TPRK)的临床效果。

方法：回顾性非随机性研究。选取2017-08/2018-05在我院接受SPT辅助的TPRK手术的近视患者260例508眼，术后随访3mo，检测患者的裸眼视力(UCVA)和等效球镜度，观察角膜上皮愈合情况，评估患者的疼痛度及满意度情况。

结果：本组患者术后5d内在配戴角膜绷带镜的状态下可以进行日常生活及一般工作，术后1、3mo UCVA(-0.080±0.0798、-0.108±0.089)均达到甚至优于术前BCVA(-0.050±0.0561)。术后5d，所有患者的角膜上皮均完全修复，术后1、3mo随访，仅3例4眼患者在裂隙灯显微镜下观察到不影响视力的haze(0～1级)。本组患者208例术后当天感觉疼痛，均于1d后缓解，3d后完全消失。术后3mo进行满意度调查显示93.0%患者非常满意。

结论：SPT辅助的TPRK术治疗近视临床效果较好，术后视力恢复快，角膜上皮重塑时间短，能很好地缓解表层手术后疼痛，患者满意度较高。

METHODS: This was a retrospective non-randomized research. There were 260 patients(508 eyes)who were underwent SPT-assisted TPRK surgery. The best corrected visual acuity(BCVA)was recorded at 1 to 2wk before surgery. The uncorrected visual acuity(UCVA)was recorded at 1mo and 3mo after surgery. Corneal epithelial growth status and haze grade were recorded after surgery. Record the degree of pain within 3d after surgery and satisfaction surveys in all patients.

RESULTS: After 1mo and 3mo, UCVA(-0.080±0.0798, -0.108±0.089)achieved or even better than preoperative BCVA(-0.050±0.0561). Corneal epithelial wounds were completely repaired in all patients during 5d after operation. In the follow-up of 1mo and 3mo after operation, the corneas of most patients are clear except for 3 cases who had haze in 0-1 grade. Very satisfied patients accounted for 93.0%.

CONCLUSION: SPT-TPRK surgery is safe. The average postoperative UCVA can reach or even exceed the preoperative average BCVA.