目的：评估可植入式Phakic角膜接触镜治疗稳定型圆锥角膜患者的疗效、安全性、稳定性和可预测性。

方法：共14例患者采用植入式Phakic角膜接触镜(IPCL)矫正屈光不正，测量了未矫正视力、最佳矫正视力、离焦曲线、对比敏感度、屈光度及可能的副作用。评估结果超过6mo。

结果：平均等效球镜度(SE)和散光在术后6mo末次检查时由术前-6.94±2.79 DS和-4.24±1.42 DC分别变为术后-0.23±0.43 DS和-1.05±0.49 DC。术前平均Snellen视力为0.18±0.10。6mo内未矫正视力和最佳矫正视力平均值分别为0.13±0.10和0.05±0.15。平均安全指数为1.11。所有眼视力均无降低，其中22眼视力提高超过1行。20眼(71.4%)屈光度在0.50 D以内，27眼(96.42%)在±1.00 D以内。术后1wk至6mo，屈光度变化为-0.23±0.43(范围： -1.00至+0.75)。6mo内角膜内皮细胞(ECL)丢失率小于5%。术后6mo眼压(IOP)为11.32±2.28 mmHg。

结论：Toric植入式Phakic角膜接触镜在矫正与稳定圆锥角膜相关的近视和近视散光方面具有有效性、安全性和可预测性。

METHODS: The uncorrected and the best corrected visual acuity, defocus curve, contrast sensitivity, refraction and possible side effects were measured in 14 patients after utilizing implantable Phakic contact lens(IPCL)to correct refractive errors. The result was assessed for more than 6mo.

RESULTS: The mean preoperative spherical equivalent(SE)and astigmatism got changed from -6.94±2.79 DS and -4.24±1.42 DC to -0.23±0.43 DS and -1.05±0.49 DC, respectively at the last examination after 6mo. Before the preoperative the mean Snellen visual acuity was 0.18±0.10 LogMAR. The mean uncorrected and the best corrected visual acuity got changed to 0.13±0.10 LogMAR and 0.05±0.15 LogMAR, respectively in 6mo. The mean safety indices were 1.11. There was no loss of visual acuity in any of the eyes and 22 eyes(78.5%)gained one or more lines. Twenty eyes(71.4%)were within 0.50 D and 27(96.42%)were within ±1.00 D of the desired spherical equivalent refraction. There was a change in manifest refraction of -0.23±0.43(range from -1.00 to +0.75)from the first week of surgery to 6mo. Contrast sensitivity got improvement value at 3 per degree(P<0.005)after Toric IPCL implantation. The total 6mo corneal endothelial cell loss(ECL)was less than 5%. Intraocular pressure(IOP)was 11.32±2.28 mmHg after 6mo.

CONCLUSION: The clinical consequences of the present study exhibit the efficacy, safety, and predictability of Toric implantable Phakic contact lens in the correction of myopia and myopic astigmatism related with stable keratoconus.