目的：比较RTVue XR和Keratograph眼表综合分析仪测量下泪河高度(LTMH)的差异，评估两种设备在初始眼以及FS-LASIK术后眼中测量LTMH的重复性和再现性。

方法：选择2019-01在广州爱尔眼科医院就诊的初始眼以及FS-LASIK术后眼各52只。分别使用RTVue XR和Keratograph眼表综合分析仪进行LTMH测量。比较两种设备测量值的差异。采用组内标准偏差(Sw)，重复测量重复度(2.77Sw)，变异系数(CoV)和组内相关系数(ICC)评价两种设备测量的重复性和再现性。

结果：初始眼组中，RTVue XR和Keratograph测量的LTMH分别为261.12±80.29、235.05±78.40μm； 平均CoV为5.55%、14.90%； 平均ICC为0.98、0.87。FS-LASIK眼组中，RTVue XR和Keratograph测量的LTMH分别为234.55±68.38、208.22±73.85μm； 平均CoV为5.29%、16.16%； 平均ICC为0.97、0.87。

结论：在初始眼及FS-LASIK术后眼中，RTVue XR测量的LTMH值较Keratograph测量值偏大约25μm，测量的信度更高。RTVue XR可以用于临床上初始眼以及FS-LASIK术后眼的LTMH的评估。

METHODS: Totally 52 virginal eyes and 52 FS-LASIK eyes were included during January 2019 in Guangzhou Aier Eye Hospital. LTMH measurements were performed using RTVue XR and Keratograph Ocular Surface Analyzer. A paired t-test was used to compare the difference between LTMH values using the two devices. The with-subject standard deviation(Sw), test-retest repeatability(2.77Sw), coefficient of variation(CoV)and intraclass correlation coefficient(ICC)were calculated to evaluate the repeatability and reproducibility.

RESULTS: In the virginal eyes group, the average LTMH obtained with RTVue XR and Keratograph were 261.12±80.29μm and 235.05±78.40μm, respectively. CoV and ICC were 5.55% and 0.98 for RTVue XR, 14.90% and 0.87 for Keratograph, respectively. In the FS-LASIK group, the average LTMH were 234.55±68.38μm and 208.22±73.85μm, respectively. CoV and ICC were 5.29% and 0.97 for RTVue XR, 16.16% and 0.87 for Keratograph, respectively.

CONCLUSION: In the virginal and FS-LASIK eyes, the LTMH value obtained with RTVue XR is 25μm greater than Keratograph. RTVue XR has a better reliability than Keratograph and can be used to measure the LTMH.