目的：分析南阳地区学龄前儿童感染性眼病病原菌分布及耐药性。

方法：回顾性分析南阳地区拟诊为学龄前儿童感染性眼病480例480眼，分析病原菌的分布及其耐药性。

结果：480份样本共培养出阳性144份，细菌培养阳性122份； 122份细菌样本中，革兰氏阳性球菌占45.9%(56/122)，以表皮葡萄球菌所占比例最高(46.4%，26/56)； 革兰氏阳性杆菌占18.9%(23/122)，以棒状杆菌所占比例最高(82.6%，19/23)。药敏结果显示：表皮葡萄球菌对多数抗生素均有不同程度耐药； 肺炎克雷伯菌对氨苄西林、哌拉西林完全耐药。

结论：南阳地区学龄前儿童感染性眼病的致病原以革兰氏阳性球菌为主，耐药率较高，临床上应根据药敏结果合理用药。

METHODS: Totally 480 cases of preschool children(480 eyes)who were diagnosed as suspected infectious eye diseases were retrospectively analyzed. The pathogens distribution and resistance were analyzed.

RESULTS: All 144 positive cultures were cultured among 480 samples, including 122 positive bacterial cultures. Among the 122 bacterial samples, Gram-positive cocci accounted for 45.9%(56/122)with the highest proportion of Staphylococcus epidermidis of 46.4%(26/56). Gram-positive bacilli accounted for 18.9%(23/122)with the highest proportion of Corynebacterium of 82.6%(19/23). Drug susceptibility results showed that Staphylococcus epidermidis had different degrees of resistance to most antibiotics, and Klebsiella pneumoniae was completely resistant to ampicillin and piperacillin.

CONCLUSION: Gram-positive cocci are the main pathogens of preschool children with infectious eye diseases in Nanyang Area, and the resistance rate is high. It is necessary to given rational use of drugs based on drug susceptibility results.