方法：回顾性分析114例158眼白内障术后干眼症患者临床资料，根据干眼症治疗方式分为研究组(rhEGF联合玻璃酸钠组)和对照组(玻璃酸钠组)。治疗4wk后评估疗效、干眼症状(干眼问卷)，检查BUT、SⅠt、FL，检测患眼泪液IL-1β、IL-6、TNF-α水平。

结果：研究组总有效率大于对照组(P<0.05)。治疗4wk后，两组BUT、SⅠt均较治疗前升高，且研究组高于对照组(P<0.01)； 两组干眼问卷评分及FL、患眼泪液IL-1β、IL-6、TNF-α水平均较治疗前降低，且研究组低于对照组(P<0.05)。

结论：加用rhEGF滴眼液治疗白内障术后干眼症可显著改善患者干眼症状、患眼泪膜稳定性、泪液分泌情况及角膜上皮细胞完整性，减轻炎症反应，疗效显著。

METHODS: The clinical data of 114 patients(158 eyes)with xerophthalmia after cataract surgery were retrospectively analyzed. According to the treatment methods of xerophthalmia, the patients were divided into study group(rhEGF+sodium hyaluronate group)and control group(sodium hyaluronate group). After 4wk of treatment, the efficacy and dry eye symptoms(dry eye questionnaire)were evaluated, and the BUT, SⅠt and FL were examined. The levels of IL-1β, IL-6 and TNF-α in tear were detected.

RESULTS: The total effective rate in study group was greater than that in control group(P<0.05). After 4wk treatment, the BUT and SⅠt in the two groups were higher than those before treatment, and the indexes in study group were higher than those in control group(P<0.01). The dry eye questionnaire score and FL and levels of tears IL-1β, IL-6 and TNF-α were lower than those before treatment, and the indexes in study group were lower than those in control group(P<0.05).

CONCLUSION: Addition of rhEGF eye drops for xerophthalmia after cataract surgery can significantly improve dry eye symptoms, tear film stability, tear secretion and corneal epithelial cell integrity, and reduce inflammatory response, and it has significant efficacy.