目的：观察Centurion超声乳化仪主控液流系统应用于白内障手术的有效性和安全性。

方法：前瞻性研究。于2018-10/12选取年龄相关性白内障(Emery核硬度分级Ⅱ～Ⅳ级)患者133例133眼，随机分为两组，试验组采用主控液流系统，对照组采用重力液流系统。术中记录累积释放能量(CDE)、抽吸时间(AT)、灌注液用量(EFU)，分别于术前和术后1d测量角膜内皮细胞计数(ECD)和中央角膜厚度(CCT)。

结果：术中试验组患者的CDE、AT、EFU明显低于对照组(均P<0.05)，术后1d试验组和对照组患者ECD均较术前轻度减少，CCT均较术前轻度增加，但两组间均无差异(2056.06±308.10cells/mm² vs 1997.26±297.55cells/mm²，532.75±12.02μm vs 531.02±13.00μm； 均P>0.05)，且两组患者术中及术后均未发生严重的眼部并发症。

结论：Centurion主控液流系统在整个手术过程中能够维持恒定的眼内压，有效提高了前房稳定性，比传统重力液流系统更加安全高效。

METHODS: One hundred and thirty-three eyes with Ⅱ-Ⅳ grades cataracts were enrolled in this randomized prospective study from October to December 2018. They were divided into two groups, the experimental group used active-fluidics configuration for cataract surgery, while the control group used gravity-fluidics configuration. Cumulative dissipated energy(CDE), aspiration time(AT)and estimated fluid used(EFU)of each patient were recorded during the operation, endothelial cell density(ECD)and central corneal thickness(CCT)were measured before and one day after operation.

RESULTS: The CDE, AT and EFU were significantly lower with the active-fluidics configuration than with the gravity-fluidics configuration(P<0.05); ECD was slightly decreased and CCT was slightly increased in both groups 1d after operation, but there was no difference between the two groups(2056.06±308.10cells/mm² vs 1997.26±297.55cells/mm², 532.75±12.02μm vs 531.02±13.00μm; P>0.05). No serious ocular adverse events related to the study devices or device deficiencies were observed.

CONCLUSION:Centurion active-fluidics configuration can maintain constant intraocular pressure during the operation, improve the stability of anterior chamber effectively. So it is safer and more efficient than traditional gravity-fluidics configuration.