[关键词]
[摘要]
年龄相关性黄斑变性是造成中老年人失明的主要原因，严重影响了患者的生活质量，但目前尚无有效疗法。随着病情的进展，视网膜色素上皮层细胞逐渐退化，并最终引起视力的不可逆性损害。诱导多能干细胞的出现提供了可供移植的视网膜色素上皮细胞来源，避免了免疫及伦理等问题，但仍然需要克服许多障碍和困难。
[Key word]
[Abstract]
Age-related macular degeneration is the main cause of blindness in middle-aged and elderly people, seriously affects the quality of life of patients, but there is no effective therapy. As the disease progresses, the retinal pigment epithelial cells gradually degenerate and eventually cause irreversible damage to vision. The emergence of induced pluripotent stem cells provides a source of transplantable retinal pigment epithelial cells, avoiding immune and ethical issues, but still needs to overcome many obstacles and difficulties.
[中图分类号]
[基金项目]
广东省省级科技计划项目(No.2017A020211028); 广东省中医药局科研课题(No.20151088)
