目的：探讨年龄相关性白内障患者角膜球面像差分布情况。

方法：回顾性系列病例研究。收集2017-08/2018-08在我院确诊为单纯年龄相关性白内障患者217例217眼。按年龄分为三组：Ⅰ组50～60岁(63眼)，Ⅱ组61～70岁(107眼)，Ⅲ组71～80岁(47眼)。使用Pentacam眼前节分析系统测量角膜参数，用Zernike analysis计算以角膜顶点为中心6mm直径范围内的患者角膜前、后表面球差，角膜前、后表面K值和角膜总球差，并分析其相关性。

结果：三组患者角膜总球差平均值为0.311±0.098μm； 角膜前表面球差和总球差组间比较有差异(F=34.434、32.896，P<0.05)。角膜前、后表面K值，后表面球差与年龄无相关性(r=0.040、0.066、0.097，P>0.05)，角膜前表面球差、角膜总球差与年龄呈正相关(r=0.506、0.509，P<0.05)。

结论：年龄相关性白内障患者角膜总球差较之前的研究结果略高，角膜前表面球差和总球差与年龄呈正相关，后表面球差与年龄无关。

METHODS: Retrospective study. Totally 217 cases of age related cataract(217 eyes)were collected in the Central Hospital of Kaifeng from August 2017 to August 2018. Patients were divided into 3 groups according to age: 50-60 years(63 eyes)in group Ⅰ, 61-70 years(107 eyes)in group Ⅱ, 71-80 years(47 eyes)in group Ⅲ. Pentacam anterior segment analysis was used to measure the anterior and posterior corneal K-readings. The corneal spherical aberration of anterior, posterior and total were calculated on an area of 6mm diameter by Zernike analysis and a descriptive study was used.

RESULTS:The Mean±SD of total corneal spherical aberration was 0.311±0.098μm for all the patients. Statically significant were found for the anterior and total corneal spherical aberration(F=34.434, 32.896; P<0.05). The anterior, posterior corneal K-readings and posterior corneal spherical aberration had no correlation with age(r=0.040, 0.066, 0.097, P>0.05). The anterior and total corneal spherical aberration were positively correlated with age(r=0.506, 0.509, P<0.05).

CONCLUSION:The total corneal spherical aberration in age-related cataract was slightly higher than that before. The anterior and total corneal spherical aberration increased with age, and then the posterior corneal spherical aberration was not.