目的：比较两种不同参数透巩膜睫状体光凝术的疗效及安全性。

方法：分析2014-01/2018-12行透巩膜睫状体光凝术(TSCP)的难治性青光眼46例46眼的临床资料，按照治疗参数的不同分为低功率组(接受低功率TSCP)和常规参数组(接受常规参数TSCP)，比较两组的降眼压效果、视力、抗青光眼药物使用情况及并发症。

结果：术前、术后1d，1wk，1、3mo两组患者眼压均无差异(P>0.05)。术后3mo，低功率组、常规参数组手术总成功率分别为87%、83%(P=1.000)。术后3mo，低功率组、常规参数组并发症发生分别为9眼(39%)、18眼(78%)(P=0.007)。术后1d低功率组患者疼痛评分低于常规参数组(P=0.007)。

结论：低功率透巩膜睫状体光凝术与常规透巩膜睫状体光凝术的降眼压效果相似，但术后疼痛更轻，并发症更少。

METHODS: A total of 46 cases with refractory glaucoma(46 eyes)who underwent TSCP from January 2014 to December 2018 were analyzed retrospectively. According to the laser parameters, all cases were divided into low-power group(treated by low-power TSCP)and conventional parameter group(treated by conventional parameter TSCP). Intraocular pressures(IOP), best-corrected visual acuity(BCVA), number of anti-glaucoma drugs and complications were observed and compared between the two groups.

RESULTS: There was no significant difference of IOP between the two groups at postoperative 1d, 1wk, 1mo and 3mo(all P>0.05). The total success rate was 87% in the low-power group while 83% in the conventional parameter group(P=1.000).The overall incidence of complications of the low-power group(39%)was lower than that of the conventional parameter group(78%)(P=0.007)at postoperative 3mo. The early postoperative pain score of the low-power group was significantly lower than that of the conventional parameter group(P=0.007).

CONCLUSION:Compared with conventional parameters, TSCP with lower power may reduce IOP similarly with less pain and fewer complications.