目的：观察小梁切除联合地塞米松离子导入治疗急性原发性闭角型青光眼(PACG)合并糖尿病的临床疗效。

方法：回顾性研究。选取我院急性PACG合并糖尿病患者42例42眼，根据术后控制炎症方式不同分为小梁切除联合地塞米松离子导入组(A组)和小梁切除联合球周注射甲泼尼龙组(B组)。比较两组患者手术前后眼压、术后前房炎症反应和并发症等。

结果：两组患者术后眼压较术前明显改善(P<0.05)，且两组患者术后前房炎症控制良好(P>0.05)，A组并发症显著少于B组。

结论：小梁切除联合地塞米松离子导入或联合球周注射甲泼尼龙，均能有效控制急性PACG合并糖尿病术后眼压和前房炎症反应，联合地塞米松离子导入降低并发症方面效果更优。

METHODS: Totally 42 eyes of 42 patients with acute PACG combined with diabetes in our hospital were selected and divided into trabeculectomy combined with iontophoresis group(group A)and trabeculectomy combined with peribulbar injection of methylprednisolone group(group B)according to different ways of controlling inflammation after surgery. Intraocular pressure, anterior chamber inflammation and complications before and after surgery were compared between the two groups.

RESULTS: The intraocular pressure of the two groups after surgery was significantly improved compared with that before surgery, and the difference was statistically significant(P<0.05). Postoperative anterior chamber inflammation was well controlled in both groups without statistical significance(P>0.05). In terms of complications, group A was significantly superior to group B.

CONCLUSION: Trabeculectomy combined with dexamethasone iontophoresis or peribulbar injection of methylprednisolone can effectively control postoperative intraocular pressure and anterior chamber inflammation in patients with acute angle-closure glaucoma complicated with diabetes mellitus. Among them, the effect of combined dexamethasone iontophoresis in reducing complications is better and patients suffer less pain.