目的：评估一种新型弱视筛查软件的有效性。

方法：2017年，在门诊招募了324名3～6岁学龄前儿童。儿童的家长独立使用弱视筛查软件判断他们是否可能患有弱视，然后所有儿童都进行专业的眼科检查。以眼科医生的诊断做对照，对弱视筛查软件的筛查敏感性和特异性进行评价。

结果：共324名儿童(176名男性，148名女性)完成了整个试验流程。专科诊断了4名弱视患儿，弱视筛查软件发现了其中3名。软件筛查的敏感性和特异性分别为75%和90%。专业诊断确诊一名弱视需要607美元，而软件筛查除了开发外，几乎0成本。

结论： 本研究表明，弱视筛查软件是一种新型简单，有效且性价比高的弱视筛查手段，尤其适合发展中国家。

METHODS: Totally 324 preschoolers aged 3-6 years old from outpatient department participated in the study in 2017. They were assessed for amblyopia by their parents, using the screening software and were reevaluated by ophthalmologists with professional eye tests. Sensitivity, specificity of the screening software were validated by comparing the results from the screening software and those from the professional tests.

RESULTS: All 324 children(176 males and 148 females)completed all of the procedures. Four amblyopes were found by professional tests. And 3 of them were detected by the screening software. The sensitivity, specificity were 75%, 90%, respectively. Professional tests cost an average of US Dollar(US$)607/case of amblyopia detected, whereas the cost was near US$ 0/case for the screening software, except the cost of software development.

CONCLUSION:The results from this pilot study indicate that the screening software for amblyopia is a simple, and highly effective, which offers a new option of amblyopia screening for developing countries.