目的：探讨不同眼内灌注液对玻璃体切割术后增殖性糖尿病视网膜病变(PDR)患者晶状体混浊程度的影响，为内眼手术灌注液的选择提供新思路。

方法：选取2018-03/2019-02于我院行玻璃体切割手术的PDR患者48例48眼，随机分为BSS灌注液组(23例23眼)和世可灌注液组(25例25眼)。手术前后均采用LOCSⅢ分级系统对晶状体混浊程度进行分级评分，采用Pentacam眼前节分析仪测定晶状体密度值及厚度值。

结果：术后3mo，两组患者晶状体LOCSIII 分级晶状体核(NC)、后囊膜(P)评分值及晶状体密度均显著高于术前(P<0.05)，而C评分值无显著差异(P>0.05)； 此外，BSS灌注液组患者晶状体厚度显著高于术前(P<0.05)，而世可灌注液组与术前无显著差异(P>0.05)，且世可灌注液组患者NC、P评分值及晶状体密度和厚度值均显著低于BSS灌注液组(均P<0.05)，但两组C评分值无差异(P>0.05)。

结论：世可灌注液可一定程度延缓玻璃体切割术后并发性白内障的发生发展。

METHODS: Totally 48 subjects(48 eyes)patients with proliferative diabetic retinopathy from March 2018 to February 2019 were enrolled in this study, randomly divided into BSS intraocular irrigating solution group(23 cases and 23 eyes)and Shike intraocular irrigating solution group(25 cases and 25 eyes). LOCS grading system Ⅲ was applied to grade lens opacity. Pentacam occipital analyzer was applied to analyze the density and thickness of lens, and the results were compared and discussed.

RESULTS:Three months after PPV,NC, P score and the density of lens in LOCSIII grade in the two groups were significantly higher than those before surgery(P<0.05), but the C score was not different significantly(P>0.05). In addition, the thickness of the lens in BSS intraocular irrigating solution group was significantly higher than that before PPV(P<0.05), but there was no significant difference in the Shike intraocular irrigating solution group(P>0.05). NC, P score, the density and thickness of lens were significantly lower in Shike intraocular irrigating solution group than those in the BSS intraocular irrigating solution group. But the C score was not different significantly between the two groups(P>0.05).

CONCLUSION: Shike intraocular irrigating solution can delay the development of postoperative complicated cataract formation.