目的：应用双通道视觉质量分析系统(OQAS Ⅱ)及生活质量量表评估高度近视中央孔型有晶状体眼后房型人工晶状体(ICL V4c)植入术后的早期客观视觉质量及视觉相关生活质量。

方法：分析就诊于我院由同一术者施行ICL V4c植入术的高度近视患者26例44眼的临床数据，包括术前及术后1wk，1、3mo的裸眼视力(UCVA)、最佳矫正视力(BCVA)、眼压、角膜内皮细胞密度(ECD)、拱高、客观散射指数(OSI)、调制传递函数截止频率(MTF cut off)、斯特列尔比(SR)、对比度为100%、20%、9%的模拟对比度视力(OV 100%、OV 20%、OV 9%)，并进行生活质量量表问卷调查。

结果：高度近视患者术后各时间点的UCVA均优于术前BCVA(P<0.001)； 术后1wk眼压较术前及术后1、3mo升高(P<0.05)； 术后1wk，1、3mo ECD均较术前减少(P<0.05)，但均在正常范围内； 拱高无明显差异(P=0.790)； 术后各时间点OSI、MTF cut off、SR、OV 100%、OV 20%、OV 9%均优于术前(P<0.001)； 生活质量问卷调查显示术后患者主观视力好，满意度高。

结论：ICL V4c植入术矫正高度近视安全有效，早期即可明显改善客观视觉质量，提高患者视觉相关生活质量，为建立ICL在高度近视患者应用中的“主客观结合综合评价体系”奠定了基础。

METHODS: Totally 26 patients(44 eyes)with high myopia were enrolled in this research. The patients were all recieved ICL V4c implantation by the same surgeon in our hospital. The evaluation items included uncorrected visual acuity(UCVA), best corrected visual acuity(BCVA), intraocular pressure, corneal endothelial cell density(ECD), vault, objective scattering index(OSI), modulation transfer function cut off frequency(MTF cut off), Strehl ratio(SR), predicted visual acuity values(OV 100%, OV 20%, OV 9%)at contrasts of 100%, 20%and 9% and vision related quality of life questionnaire. All measurements were performed preoperative and 1wk, 1mo, 3mo postoperatively.

RESULTS: Compared with preoperative BCVA, for the high myopia patients, the 1wk, 1mo and 3mo UCVA postoperative were better at all time points, and the differences were statistically significant(P<0.001). Postoperative 1wk intraocular pressure was higher than that in preoperative and postoperative 1mo and 3mo(P<0.05). Postoperative corneal endothelial cell counts at all time points were lower than that in preoperative(P<0.05), but all within the normal range. No significant difference was found in vault(P=0.790). Compared with preoperative OSI, MTF cut off, SR, OV 100%, OV 20% and OV 9%, the situation improved at postoperative 1wk, 1mo and 3mo, with statistical significance(P<0.001). The vision related quality of life questionnaire showed that all patients had high satisfaction in the good subjective visual acuity after operation.

CONCLUSION: ICL V4c implantation is safe and effective in correcting high myopia. The objective visual quality and vision related quality of life of patients with high myopia was significantly improved after ICL V4c implantation in the early stage. The research laid a foundation for the establishment of “the comprehensive evaluation system of subjective and objective combination” of ICL in the application of high myopia.