目的：比较Pentacam、IOL Master和角膜地形图测量低中度青少年近视患者角膜曲率的差异性和一致性。

方法：前瞻性临床研究。选取2019-01/10在南京医科大学附属眼科医院就诊的低中度青少年近视患者291例291眼，其中低度近视患者141例141眼，中度近视患者150例150眼，分别采用Pentacam、IOL Master及角膜地形图检查角膜曲率(K₁、K₂、K_m)和角膜散光(J₀、J₄₅)情况，分析三种仪器测量结果的差异性、相关性和一致性。

结果：差异性分析结果显示，Pentacam和角膜地形图测量低度和中度青少年近视患者J₄₅的测量值无差异(P>0.05)； Pentacam和IOL Master测量低度近视患者J₀的测量值无差异(P>0.05)； Pentacam和角膜地形图测量低度近视患者K₂、中度近视患者J₀的测量值均无差异(P>0.05)； 三种仪器测量低度和中度青少年近视患者其他测量值均有差异(P<0.05)。相关性分析结果显示，三种仪器测量结果两两分析均呈正相关(r=0.545～0.997，均P<0.001)。Bland-Altman一致性分析结果显示，三种仪器的检测结果具有较好的一致性。

结论：Pentacam、IOL Master和角膜地形图三种仪器的检测结果具有较好的一致性，均可用于低中度近视患者角膜塑形镜验配前的参数检测，其中Pentacam与角膜地形图差异性最小，但三种仪器是否可以互做替代仍需结合临床实际应用。

METHODS: A prospective clinical study. 291 adolescent patients(291 eyes)with low and moderate myopia who underwent orthokeratology in the Affiliated Eye Hospital of Nanjing Medical University from January 2019 to September 2019 were selected. Among them, 141 cases(141 eyes)were low myopia and 150 cases(150 eyes)were moderate myopia. Corneal curvature(K₁, k₂, K_m)and corneal Astigmatism(J₀, J₄₅)were examined by Pentacam, IOL Master, and corneal topography. And then the difference, correlation and consistency of the measurement results of three instruments were analyzed.

RESULTS: Differences analysis showed that in the measurement of J₄₅, there was no difference between Pentacam and corneal topography(P>0.05)in patients with low and moderate myopia; in the measurement of J₀,there was no difference between Pentacam and IOL Master(P>0.05)in patients with low myopia; in the measurement of K₂,there was no difference between Pentacam and corneal topography(P>0.05)in patients with low myopia; in the measurement of J₀,there was no difference between Pentacam and corneal topography(P>0.05)in patients with moderate myopia. But there were significant differences in other measurements among three instruments(P<0.05). Pearson correlation analysis showed that K₁, K₂, K_m, J₀, and J₄₅ were highly correlated among three instruments(r=0.545-0.997, all P<0.001). Bland-Altman consistency analysis showed that three instruments had good consistency.

CONCLUSION: Pentacam, IOL Master and corneal topographic have good consistency and can be used as a mutual reference before orthodontic fitting of low and moderate myopia patients. The measurement difference between Pentacam and corneal topography is the smallest among three instruments, but whether three instruments can be replaced by each other needs to be considered in combination in clinical application.