目的：分析温州地区近视儿童的骨龄、年龄、身高、体质量、眼生物学参数之间的关系。

方法：收集温州地区近视儿童410例820眼，年龄5～11岁，测量每位儿童身高、体质量、骨龄、眼轴长度(AL)、计算体质量指数(BMI)。快速散瞳后医学验光测得屈光度数，并将其换算为等效球镜度数(SE)。对每个年龄段的儿童按骨龄差(生物年龄-生活年龄)进行分组，分别统计各个组别的近视占比，并比较不同骨龄差组间近视占比。将近视儿童按骨龄差进行分组，统计每个组别内男、女性别的占比，并比较男童、女童间的近视占比。

结果：5～11岁近视儿童的年龄与身高、体质量、BMI、SE、眼轴有一定相关性(r_s=0.853、0.776、0.291、-0.274、0.312，均P<0.05)，与骨龄差无相关性(r_s =0.045，P>0.05)。在5～11岁的近视儿童中，40.5%儿童骨龄超前，40.2%儿童骨龄差在正常范围，19.3%儿童骨龄落后(χ²=21.576，P<0.05)。在5～11岁的近视儿童中，男童占46.3%，女童占53.7%(χ²=17.322，P<0.01)，其中在骨龄超前的儿童中，女童的比例高于男童。

结论：温州地区5～11岁近视儿童的年龄与身高、体质量、BMI、SE、眼轴有一定相关性。低龄近视儿童中有较多儿童骨龄超前，尤其是女童。

METHODS: Totally 410 cases(820 eyes)of myopic children with age distribution of 5-11 years old were collected. The height, weight, bone age and axial length(AL)of each child were measured, and body mass index(BMI)was calculated. Refractive was measured by medical optometry after rapid mydriasis, and the spherical equivalent(SE)was calculated. Children of each age group were divided into groups according to bone age difference(biological age-life age), and the prevalence of myopia in each group was statistically analyzed and compared among different bone age groups.

RESULTS: There was an association among the age, height, weight, BMI, SE and axis length(r_s=0.853, 0.776, 0.291, -0.274 and 0.312; P<0.05). There was no significant correlation between the age and the bone age(r_s=0.045, P>0.05). 40.5% of myopic children are ahead of their bone age, 40.2% of them are in the normal range, 19.3% of them are behind(χ²=21.576, P<0.05). Among the myopic children aged 5-11, 46.3% were boys and 53.7% were girls(χ²=17.322, P<0.01). The proportion of girls was much higher than boys in children with advanced bone age.

CONCLUSION: There was an association between the age and height, weight, BMI, SE, axis length in Whenzhou. Among the children with low age myopia, there are more children with advanced bone age, especially girls.