目的：探讨波及黄斑区的孔源性视网膜脱离(RRD)行巩膜扣带手术前后黄斑区三维光学相干断层扫描图像(3D-OCT)特征，分析其与视力的相关性。

方法：回顾性系列病例，30例30眼波及黄斑区的RRD行巩膜扣带术治疗的临床资料，在术后2d，2wk，1、3、6mo随诊时双眼均行3D-OCT检查，观察椭圆体带(EZ)、外界膜(ELM)、黄斑区视网膜下液高度(SRFH)、黄斑中心凹视网膜厚度(CRT)的变化，分析其与术后最佳矫正视力(BCVA)的关系。

结果：术前，术后2d，2wk，1、3、6mo SRFH、CRT、BCVA均有差异(P<0.01)，术后SRFH、CRT都有不同程度降低，术后BCVA都有不同程度升高，组内两两对比：除SRFH(2wk vs 1mo，P>0.05)、CRT(2d vs 2wk，P>0.05)、BCVA(2d vs术前，2wk vs 术前，P>0.05)无统计学意义外，其余各项间的比较均有统计学意义(P<0.05)。EZ、ELM形态可分为：A：EZ和ELM均连续(EZ+ELM+)，9眼； B：EZ断裂和ELM连续(EZ-ELM+)，7眼； C：EZ连续和ELM断裂：EZ+ELM-，6眼； D：EZ和ELM均断裂(EZ-ELM-)，8眼，术后6mo上述4种类型的BCVA分别为0.15±0.04、0.50±0.06、0.54±0.05、0.59±0.09(F=87.210，P<0.05)，两两比较：除C vs B和C vs D差异无统计学意义(P>0.05)外，其余各组间的比较差异均有统计学意义(P<0.05)。术后2d的SRF发生率为87%，术后6mo仍有46.6%患者存在持续性SRF。术后CRT与术后SRFH具有正相关关系。

结论：巩膜扣带术后黄斑微结构呈动态改变，SRF影响可能表现为BCVA延迟恢复，随着SRF缓慢吸收，CRT逐渐降低，BCVA逐渐升高； ELM或EZ连续提示有较好的BCVA，而ELM断裂可能提示视觉质量更差。

METHODS: Retrospective case review, the clinical data of scleral buckling in 30 eyes of 30 cases of RRD involving macular area were analyzed retrospectively. The changes of ellipsoid zone(EZ), external 1imiting membrane(ELM), subretinal fluid(SRF)and central retinal thickness(CRT)were observed and the relationship between them and best corrected visual acuity(BCVA)was analyzed by 3D-OCT at 2d, 2wk, 1, 3 and 6mo after operation.

RESULTS: Postoperative SRFH and CRT showed a descended trend. Postoperative BCVA showed an ascendant trend. Multiple comparisons: there were significant difference in each groups except SRFH(2wk vs 1mo, P>0.05), CRT(2d vs 2wk, P>0.05), BCVA(2d vs preoperation, 2wk vs preoperation, P>0.05). There are four forms of EZ and ELM::9 eyes, intact ELM and EZ(EZ+ELM+); B: 7 eyes, intact ELM with disrupted EZ:(EZ-ELM+); AC: 6 eyes, intact EZ with disrupted ELM:(EZ+ELM-); D: 8 eyes, disrupted ELM and EZ:(EZ-ELM-), the BCVA of the above four types are 0.15±0.04, 0.50±0.06, 0.54±0.05 and 0.59±0.09, there were significant difference in each groups except(C vs B, P>0.05)and(C vs D, P>0.05). The incidence of SRF was 87% 2d after operation, 46.6% patients had persistent SRF at 6mo after operation. Postoperative CRT was positively correlated with postoperative SRFH.

CONCLUSION: After scleral buckling, the macular microstructure showed dynamic changes. The effect of SRF may be manifested as BCVA delayed recovery. With the slow absorption of SRF, CRT decreased and BCVA increased. The intact ELM or EZ shows better vision, but the disrupted ELM means worse vision.