目的：探讨泪道探通术联合妥布霉素滴眼液治疗先天性泪囊炎的临床疗效。

方法：选取2017-01/2019-06来我院就诊的先天性泪囊炎患儿228例250眼作为研究对象，年龄为6月龄～3岁。按年龄分为3组：6月龄～<1岁133例149眼，1～<2岁62例64眼，2～3岁33例37眼。三组均实施表面麻醉下泪道探通术联合术后妥布霉素滴眼液治疗。

结果：先天性泪囊炎患儿中6月龄～<1岁治愈率为97.3%(145/149)，1～<2岁治愈率为92.2%(59/64)，2～3岁治愈率为83.8%(31/37)，无不良事件发生。三组患儿治愈率比较，6月龄～<1岁患儿治愈率最高(P=0.009)。

结论：泪道探通术治疗先天性泪囊炎疗效显著，术后联合妥布霉素滴眼液安全可靠。以6月龄～1岁为最佳治疗时机，其手术操作简单，并发症少，具有较高的临床价值。

METHODS: A total of 228 children(250 eyes)aged from 6mo-3a with congenital dacryocystitis treated in our hospital from January 2017 to June 2019 were included. They were assigned into three groups by age: 133 patients(149 eyes)aged from 6mo-1a(Group A), 62 patients(64 eyes)aged from 1-2a(Group B), and 33 patients(37 eyes)aged from 2-3a(Group C). All patients received lacrimal duct probing in surface anesthesia combined with postoperative tobramycin eye drops.

RESULTS: The probing cure rates of congenital dacryocystitis among there groups were 97.3%(Group A), 92.2%(Group B)and 83.8%(Group C), respectively. No adverse events reported. Through comparison of these three groups, the cure rate of children from 6mo-1a was the highest. The difference was statistically significant(P=0.009).

CONCLUSION: Lacrimal duct probing is effective in the treatment of congenital dacryocystitis, and it is safe and reliable to combine tobramycin eye drops(TOBREX)after surgery. The best time for treatment is 6mo-1a. The operation is simple, less complication, with high clinical value.