硒是哺乳动物所必需的一种微量元素，广泛存在于人体多个组织和器官中，主要以硒代半胱氨酸的形式发挥其生物学功能，在提高人体免疫力、改善心肌缺血、减轻氧化应激反应等多方面发挥着重要作用。眼作为人体中含硒较多的视觉器官，多种眼部疾病都与硒及硒蛋白密切相关，本文从硒及硒蛋白在眼表疾病、白内障、眼底疾病、甲状腺相关眼病的生物学功能研究方面总结，为研究硒及硒蛋白在眼部的作用提供有价值的参考资料。

Selenium is an essential microelement required as a nutrient by human organism to perform important biological functions, mainly in the form of selenocysteine. It plays an important role in improving human immunity and the myocardial nutritional blood flow, and preventing oxidative stress. Various ocular diseases are closely associated with selenium and selenoprotein due to the presence of high concentration of selenium. This article mainly aims to review the present research advance of biological functions of selenium and selenoprotein in ocular diseases, and provide some valuable reference for deeper study of selenium in human eyes.

湖北省卫生健康委员会2019～2020年度青年人才项目(No.WJ2019Q024)