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[摘要]
视网膜大动脉瘤(RAM)又称孤立性大动脉瘤,是一种获得性的视网膜血管异常,其特征是后极部视网膜小动脉呈梭形或圆形扩张,形成一个或多个大动脉瘤,大多数动脉瘤位于视网膜颞侧血管上,临床上早期多无症状,若瘤体破裂出血累及黄斑可出现突然发生的中心暗点和视力下降,出血可位于玻璃体腔、玻璃体后界膜下、视网膜内界膜下、视网膜内和视网膜下等部位。针对RAM的治疗方法有视网膜激光光凝术、玻璃体切除手术、玻璃体内或视网膜内注射组织纤溶酶原激活物、抗VEGF治疗等。本文结合国内外研究的最新进展,对RAM的治疗方法进行讨论和展望。
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[Abstract]
The retinal arterial macroaneurysm, also known as isolated aneurysm, is an acquired retinal vascular abnormality, which is characterized by fusiform or circular dilatation of the posterior polar retinal arteries, forming one or more aneurysms. Most of aneurysms are located on the temporal vessels of the retina. There are no clinical symptoms in the early stage. If the tumor ruptures and hemorrhage involving the macula, may suddenly appear central dark spots and vision loss. The hemorrhage may be located in the vitreous cavity, under the posterior vitreous boundary membrane, under the retinal inner boundary membrane, and subretinal region. Treatments for RAM include retinal laser photocoagulation, vitrectomy, intravitreal or intraretinal injection of tissue plasminogen activator, and anti-VEGF agent. In this paper, the latest research progress in the treatment of RAM is discussed and prospected.
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