[关键词]
[摘要]
白细胞介素-17(IL-17)是自身免疫疾病和许多炎性疾病的重要促炎因子。越来越多的研究表明,IL-17在眼部疾病的发病机制中也起到关键作用。本文对IL-17在角膜炎、干眼、葡萄膜炎、糖尿病视网膜病变、年龄相关性黄斑变性中的作用及机制进行综述,为治疗这类疾病提供新的思路和靶点。
[Key word]
[Abstract]
Interleukin-17(IL-17)is an important pro-inflammatory factor in autoimmune diseases and many inflammatory diseases. Studies have shown IL-17 plays a vital role in the pathogenesis of eye disease. This paper reviews the function and mechanism of IL-17 in keratitis, dry eye, uveitis, diabetic retinopathy, and age-related macular degeneration, providing new ideas and targets for the treatment of these diseases.
[中图分类号]
[基金项目]
云南省基础研究计划(No.2018FE001-265); 昆明医科大学创新基金项目(No.2020S226)