目的：分析比较IOL Master 700与Pentacam在不同年龄段白内障患者角膜生物参数的差异性、相关性及一致性。

方法：横断面研究。收集2020-02/09就诊于潍坊眼科医院的白内障患者87例162眼，其中男44例80眼，女43例82眼，平均年龄61.2±9.87岁，将患者按年龄分为四组，A组(40～50岁)17例32眼，B组(51～60岁)25例47眼，C组(61～70岁)28例53眼，D组(71～80岁)17例30眼，分别用IOL Master 700和Pentacam测量各组白内障患者术前角膜生物参数，记录为平坦轴角膜曲率(K1)、陡峭轴角膜曲率(K2)、平均角膜曲率(Km)、角膜散光度数、前房深度(ACD)、中央角膜厚度(CCT)。分析两种生物测量仪器间在不同年龄组测量结果的差异性、相关性及一致性。

结果：两种仪器测量C组患者角膜散光度数及D组患者K1、角膜散光度数之间有差异(t=2.746、-2.582、2.637，均P<0.05)。Pearson相关性分析显示两种仪器在测量四组患者参数时有良好的相关性。Bland-Altman分析结果显示IOL Master 700与Pentacam测量四组患者K1、K2、Km、角膜散光度数、ACD、CCT的一致性较好。

结论：IOL Master 700与Pentacam在测量40～60岁白内障患者的角膜生物参数方面无明显差异，在61～70岁患者时散光度数有差异，在71～80岁患者时散光度数、K1值有差异，测量结果显示两种仪器有良好的相关性。总体来说，两种检查设备的一致性较好，角膜散光度数及角膜曲率要综合分析数据进行选择。

METHODS: Cross-sectional study. A total of 87 cataract patients(162 eyes)in Weifang Eye Hospital from February to September 2020 were collected, including 44 males(80 eyes)and 43 females(82 eyes)(age 61.2±9.87 years). The patients were divided into four groups: group A \〖17 cases(32 eyes), 40-50 years old\〗, group B \〖25 cases(47 eyes), 51-60 years old\〗, group C \〖28 cases(53 eyes), 61-70 years old\〗, and group D \〖17 cases(30 eyes), 71-80 years old\〗. The preoperative corneal biological parameters of cataract patients were measured by IOL Master 700 and Pentacam, and the flat axis corneal curvature(K1), steep axis corneal curvature(K2), mean corneal curvature(Km), corneal astigmatism, anterior chamber depth(ACD)and central corneal thickness(CCT)were recorded. The difference and correlation of measurement results between two kinds of biometric instruments in different age groups were analyzed.

RESULTS: Except for the corneal astigmatism in group C and K1 and corneal astigmatism in group D, there were significant differences between the two instruments(t=2.746, -2.582, 2.637, all P<0.05), but there was no significant difference in other parameters among the four groups. Pearson correlation analysis showed that there was a good correlation between the two instruments in measuring the parameters of the four groups of patients. The results of Bland-Altman analysis showed that there was a good consistency between IOL Master 700 and Pentacam in measuring K1, K2, Km, corneal astigmatism, ACD and CCT in the four groups.

CONCLUSION:There was no significant difference between IOL Master 700 and Pentacam in the measurement of corneal biological parameters in cataract patients aged 40-60 years, but there was significant difference in astigmatism between 61-70 years old, astigmatism and K1 value in 71-80 years old patients. Pearson correlation analysis showed that there was a good correlation between the two instruments. Generally speaking, the consistency of the two kinds of examination equipment is good, and the corneal astigmatism and corneal curvature should be selected by comprehensive analysis of the data.