目的：探讨多焦点设计的硬性角膜接触镜对近视患者双眼视功能的影响。方法：自身前后对照研究。于2020-07/08在川北医学院招募近视学生15人作为试验者，试验者首先配戴框架眼镜行双眼视功能检查，然后分别配戴单焦点与多焦点硬性角膜接触镜(间隔1wk)，每种镜片配戴2wk后行双眼视功能检查。采用单因素方差分析比较多焦点硬性角膜接触镜(MFRGP)、单焦点硬性角膜接触镜(SVRGP)和框架眼镜双眼视功能的差异。结果：三种镜片立体视、远距水平隐斜、远距正融像性聚散、远距负融像性聚散、近距正融像性聚散、聚散灵活度、集合近点、调节幅度、调节灵活度、负相对调节比较均无差异(P>0.05)。与框架眼镜相比，配戴MFRGP近距水平隐斜、近距负融像性聚散、调节滞后、正相对调节增大，AC/A降低(P=0.023、0.048、0.001、0.013、0.046)； 与SVRGP相比，MFRGP近距水平隐斜、调节滞后、正相对调节增大，AC/A降低(P=0.014、<0.001、0.001、0.009)。结论：配戴MFRGP会引起近距水平隐斜、调节滞后、正相对调节增大和AC/A降低，这些变化可能对配戴者近距离用眼产生一定影响，在临床应用中要考虑这些预期的变化，以便正确评估和管理患者。

AIM: To investigate the effect of rigid contact lenses with multifocal design on binocular visual function in myopic patients. METHODS: A self-control study before and after. Fifteen myopic students of North Sichuan Medical College were recruited as test persons between July and August 2020. The subjects first wore framed glasses for binocular visual function examination, then wore single vision and multifocal rigid contact lenses(1wk apart), and binocular visual function examination was performed after wearing each lens for 2wk. One-way analysis of variance was used to compare the binocular visual function of multifocal rigid contact lens, single vision rigid contact lens and frame glasses.RESULTS: There were no significant differences among the three lenses in stereopsis, far horizontal phoria, far positive fusional vergence, far negative fusional vergence, near negative fusional vergence, convergence and dispersion flexibility, convergence near point, adjustment magnitude, adjustment flexibility and negative relative adjustment(P>0.05). Compared with frame glasses, multifocal rigid contact lenses had significant difference in near horizontal phoria, near positive fusional vergence, accommodation lag, positive relative accommodation increased and AC/A decreased(P=0.023,0.048,0.001,0.013,0.046); Compared with single vision rigid contact lenses, multifocal rigid contact lenses had significant difference in near horizontal phoria, accommodation lag, positive relative accommodation increased and AC/A decreased(P=0.014,<0.001,0.001,0.009).CONCLUSION:Wearing multifocal rigid contact lenses can lead to near horizontal phoria, accommodation lag, positive relative accommodation increase and AC/A decrease, which may have some influence on proximal use of eyes. These expected changes should be considered in clinical application in order to evaluate and manage patients correctly.

教育部留学回国人员科研启动基金{No.教外司留[2010]1174号}; 南充市2020年市校科技战略合作专项(No.20SXQT0152)