方法：前瞻性研究。收集2018-09/2019-05在新疆军区总医院北京路医疗区眼科诊断为原发性翼状胬肉患者共150例150眼，依次纳入本研究，奇数者行CAT，偶数者行LCAT，术前，术后1、3、6mo，1a完成泪膜破裂时间(TBUT)、SchirmerⅠ试验(SⅠt)和眼表疾病指数(OSDI)，结果进行统计学分析。

结果：患者129例129眼完成术后1a随访，CAT组64例64眼，复发4眼(6.2%)； LCAT组65例65眼，复发3眼(4.6%)，两组复发率无差异(P=0.718)。CAT组和LCAT组TBUT、SⅠt和OSDI评分术前和术后1、3、6mo，1a均有差异(P<0.05)，术后1mo和术后3、6mo，1a均有差异(P<0.05)，术后3、6mo和术后1a均无差异(P>0.05)。CAT组和LCAT组不同时间点TBUT、SⅠt和OSDI评分均无差异(P>0.05)。

结论：CAT和LCAT均能有效治疗原发性翼状胬肉，术后复发率低且相近，两种手术方式改善原发性翼状胬肉术后泪膜功能的程度相近。

METHODS: In a prospective study, 150 patients(150 eyes)diagnosed with primary pterygium were collected in Beijing road medical area of Xinjiang Military Region General Hospital from September 2018 to May 2019. The 150 patients enrolled in the study in turn, and divided into two groups by the odd and even number. The odd number underwent CAT and the even number underwent LCAT. Respectively before surgery and 1, 3, 6mo and 1a after surgery, tear film break-up time(TBUT), SchirmerⅠtest(SⅠt)and ocular surface disease index(OSDI)were checked. The date were compared and analyzed.

RESULTS:Totally 129 patients(129 eyes)completed the follow-up of 1a, including 64 patients(64 eyes)from the CAT group and 65 patients(65 eyes)from the LCAT group. Four patients(4 eyes, recurrence rate 6.2%)in the CAT group and 3 patients(3 eyes, recurrence rate 4.6%)in the LCAT group developed recurrence. However, there was no significant in recurrence rate between CAT group and LCAT group(P=0.718). There were significant differences between before surgery and after surgery in each group(P<0.05), and there were significant differences between 1mo after surgery and 3, 6mo and 1a after surgery in each group(P<0.05), while there was no significant different among 3, 6mo and 1a after surgery in each group in TBUT, SⅠt and OSDI(P>0.05). Also there was no significant different between CAT group and LACT group in each time in TBUT, SⅠt and OSDI(P>0.05).

CONCLUSION:Both CAT and LCAT could effectively treat primary pterygium with low and similar recurrence rate, and the degree of improvement of tear film after primary pterygium operation is similar between the two surgical methods.