目的：分析2010～2019年国家自然科学基金对白内障研究的资助情况，探讨近期白内障基础研究的发展重点，为白内障领域科研人员了解专业基础研究的进展和申请资助提供参考信息。

方法：统计2010～2019年国家自然科学基金对白内障领域研究的资助项目，对获得资助的项目类别、项目名称、经费数额、申请单位和地区、批准年度及关键词等进行统计和分析。

结果：近十年来，白内障研究的项目数及受助金额分别占眼科学总数的9.35%和9.72%。眼科学和白内障研究的项目数量及受助金额总体呈波浪式上升趋势。立项项目中的关键词逐渐增多，且愈发倾向于机制研究。计算机辅助技术、TALEN技术和全外显子测序技术等的发展，使得白内障研究整体呈现出医学与其他学科融合的趋势。华东地区，尤其上海市项目数量及受助经费位居各省市首位。各项目类别中，数量及经费均为面上项目最多，近几年青年科学基金项目数量强势崛起，甚至在某些领域超过面上项目。

结论：2010～2019年白内障研究的热点趋向于多样化，多学科的融合以及新技术新方法的运用为显著特点。资助力度和研究水平呈现地区发展不平衡。

AIM: To analyze the funding status of cataract research funded by National Natural Science Foundation of China from 2010 to 2019, and discuss the development focus on basic cataract research in the near future, so as to provide reference information for researchers in the field of cataract to understand the progress of basic research and apply for funding.

METHODS: The cataract research projects funded by the National Natural Science Foundation of China from 2010 to 2019 were counted. The categories of funded projects, project title, fund amount, applicant unit and region, approved year and key words were statistically analyzed.

RESULTS: In the past ten years, the number of cataract research projects and the amount of funding accounted for 9.35% and 9.72% of the total amount of the whole ophthalmology area respectively. The number of projects in ophthalmology and cataract research and the amount of aid received generally showed a wavy upward trend. The key words in the project setup are gradually increasing, and more and more inclined to mechanism research. With the development of computer aided technology, TALEN technology and total exon sequencing technology, cataract research presents a trend of integration of medicine and other disciplines. East China, especially Shanghai, ranks first in terms of the number of projects and funds received. Among the categories of projects, the number and funding are the largest among the general projects. In recent years, the number of the Youth Science Foundation projects has risen strongly, and even exceeds the general projects in some areas.

CONCLUSION: The focus of cataract research from 2010 to 2019 tends to be diversified. The integration of multi-disciplines and the application of new techniques and methods are prominent features. The fund amount and the level of research are unbalanced in regional development.

国家自然科学基金面上项目(No.81873674,82070947); 陕西省重点研发计划项目(No.2021ZDLSF02-08)