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[摘要]
垂体腺瘤是颅内最常见的良性肿瘤,其症状主要为视功能受损和内分泌激素紊乱。由于垂体与视交叉的特殊位置关系,视力下降和视野缺损多为首发症状,患者常常首诊于眼科。视野检查和光学相干断层扫描(OCT)可判断视野缺损程度和眼底情况,电生理检查可明确视神经是否受损,均可作为垂体腺瘤患者视功能的评估指标。磁共振作为影像学工具,其衍生技术——功能性磁共振,近年来用于研究垂体腺瘤瘤体质地及视神经完整性。此类全面详细的检查可以帮助患者明确最佳治疗时机,提高生活质量。本文针对眼科各项检查(视野、OCT和电生理)和功能性磁共振在垂体腺瘤中的应用进行简要综述。
[Key word]
[Abstract]
Pituitary adenoma, the most common benign tumor in brain, its symptoms mainly include impaired visual function and endocrine hormone disorder. Visual acuity decline and visual field defect are the first symptoms, because of the special position of pituitary and optic chiasma, patients are often first seen in the ophthalmology department. Visual field examination and optical coherence tomography(OCT)can determine the degree of visual field defect and fundus condition. Electrophysiology examination can determine whether the optic nerve is damaged. All of them can be used as evaluation indexes of visual function in patients with pituitary adenoma. As an imaging tool, functional magnetic resonance, a derivative technique, has been used to study the texture of pituitary adenoma and optic nerve integrity in recent years. These comprehensive and detailed examinations can determine the best time for treatment and improve quality of life for patients. This article reviews the application of ophthalmic examination(visual field, OCT and electrophysiology)and functional magnetic resonance in pituitary adenoma.
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