目的：应用视疲劳调查量表调查调节性视疲劳患者的视疲劳情况及治疗前后评分差异，评价其在该人群中的信度、效度及反应度。

方法：对112例上海中医药大学附属曙光医院眼科就诊及线上招募的调节性视疲劳患者，使用视疲劳调查量表进行调查，再随机抽取48例调查对象于1wk后重测，采用多种信度、效度及反应度指标对量表进行评价。

结果：量表条目的总体Cronbach's α系数为0.91； 分半信度系数为0.86； 量表总分的重复测量相关系数为0.74，前后无差异(P>0.05)； 验证性因子分析结果表明三因子结构模型绝对拟合指数χ²/df<2.0，RMSEA=0.08； 相关分析中各维度总分和量表总分的相关系数分别为0.92、0.90、0.83； 标准关联效度分析显示组间有差异(P<0.01)。反应度分析显示治疗前后有差异(P<0.01)。

结论：ASS量表用于调节性视疲劳的临床评价具有较高的信度、效度及反应度，是视疲劳人群临床研究或筛检的有效工具。

AIM: To investigate the visual fatigue of patients with accommodative asthenopia and the difference in scores before and after treatment by using the asthenopia survey scale(ASS), and to evaluate its reliability, validity and responsiveness in this population.

METHODS: A total of 112 patients with accommodative asthenopia were admitted to the department of ophthalmology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine and recruited online were investigated using the ASS questionnaire, and 48 subjects were randomly selected and retested 1wk later. A variety of reliability, validity and responsiveness indicators were used to evaluate the scale.

RESULTS: The overall Cronbach's α coefficients of the scale entries was 0.91; The split-half reliability coefficients was 0.86; Repeated measurement correlation coefficient of the scale total score was 0.74, there was no significant difference before and after(P>0.05); The results of confirmatory factor analysis showed that the absolute fit index of the three-factor structural model was χ²/df<2.0, RMSEA=0.08; The correlation coefficients of each dimension's total score and the scale's total score were 0.92, 0.90 and 0.83 respectively; The standard association validity analysis showed statistically significant differences between groups(P<0.01). Response analysis was statistically significant before and after treatment(P<0.01).

CONCLUSION: The ASS has high reliability, validity and responsiveness in the clinical evaluation of accommodative asthenopia, and it's an effective tool for clinical research and screening of asthenopia in this population.

浙江省自然科学基金资助项目(No.LQ19H270004); 浙江省中医药管理局科研基金项目(No.2018ZB058); 上海市进一步加快中医药事业发展三年行动计划(2014年-2016年)建设项目(No.ZY3-JSFC-1-1019)