目的：观察有晶状体眼后房型人工晶状体(ICL/TICL V4c)植入术后拱高的早期变化趋势并分析相关影响因素。

方法：回顾性研究。选取2020-10/2021-03于兰州华厦眼科医院接受ICL/TICL V4c植入术患者49例98眼。收集患者术前等效球镜度数(SE)、眼压、眼轴、前房深度(ACD)、晶状体厚度(LT)、中央角膜厚度、前房角(ACA)、前房容积(ACV)、角膜白到白直径(WTW)、平均角膜曲率K1、K2，术中植入的ICL尺寸，术后1、3d，1wk，1mo用AS-OCT测量患者拱高(vault)。按术后1mo拱高值大小分为低拱高组(<250μm)12眼、正常拱高组(250～750μm)62眼、高拱高组(>750μm)24眼，分析影响术后拱高的因素。

结果：术后1、3d，1wk，1mo平均拱高值分别为591.05±293.44、599.62±309.78、592.22±301.49和586.69±285.63μm。术后1mo不同拱高间WTW、ACA、ACV、ACD、ICL尺寸、LT有差异(均P<0.05)。术后1mo拱高的回归方程=-3142.19+388.25×WTW+10.40×ACA-301.63×LT，R、R²、调整R²分别为0.674、0.454、0.436。WTW对术后1mo拱高影响最大(β=0.47，P<0.001)，其次为LT(β=-0.34，P<0.001)和ACA(β=0.17，P=0.047)。

结论：WTW、ACA、LT是影响和预测ICL/TICL V4c植入术后1mo拱高的主要因素。

METHODS:In this retrospective study, a total of 49 patients(98 eyes)who underwent ICL/TICL V4c implantation in the Lanzhou Huaxia Eye Hospital from October 2020 to March 2021 were enrolled. Preoperative ocular biometric parameters were collected, including spherical equivalent(SE), intraocular pressure, axial length, anterior chamber depth(ACD), lens thickness(LT), central corneal thickness, anterior chamber angle(ACA), anterior chamber volume(ACV), white to white corneal diameter(WTW), mean keratometry K1 and K2, and intraoperative implantation size of ICL. The vault was measured by anterior segment optical coherence tomography(AS-OCT)at 1, 3d, 1wk and 1mo after surgery. The patients were divided into insufficient vault group(<250μm, 12 eyes), normal vault group(250-750μm, 62 eyes)and excessive vault group(>750μm, 24 eyes)according to the vault at 1mo after surgery. The factors affecting the postoperative vault were analyzed.

RESULTS:The mean vault values at 1 and 3d, 1wk and 1mo after surgery were 591.05±293.44, 599.62±309.78, 592.22±301.49 and 586.69±285.63μm, respectively. There were significant differences in WTW, ACA, ACV, ACD, ICL size and LT at 1mo after surgery(all P<0.05). The regression equation of vault at 1mo after surgery was as follows: vault(μm)=-3142.19+388.25×WTW+10.40×ACA-301.63×LT(R=0.674, R²=0.454, adjusted R²=0.436). WTW had the greatest influence on vault at 1mo after surgery(β=0.47, P<0.001), followed by LT(β=-0.34, P<0.001)and ACA(β=0.17, P=0.047).

CONCLUSION:WTW, ACA and LT were the main factors that affected and predicted the vault at 1mo after ICL/TICL V4c implantation.