目的：评估中国新疆和田地区居民干眼的患病率和潜在的相关危险因素。

方法：2019-01/09在中国新疆和田地区采取立意抽样的方法选取105个村18～98岁居民共计6 027人作为受试者，并进行横断面研究。调查者采用眼表疾病指数(OSDI)问卷的方式收集干眼主观症状，检查荧光素染色泪膜破裂时间(FBUT)及泪液分泌试验(Schirmer Ⅰ试验)来收集客观体征，从而分析干眼患病率及其危险因素。

结果：从中国新疆和田地区居民中招募18～98岁共6 339名受试者进行相关眼部检查和问卷调查，其中有效问卷6 027份，有效回收率为95.08%。6 027名受试者中干眼检出率为40.37%(2 433/6 027)，其中男性、女性干眼检出率分别为36.47%(846/2 320)、42.81%(1 587/3 707)； 18～24岁、25～34岁、35～44岁、45～54岁、55～64岁、≥65岁干眼检出率分别为13.77%、15.67%、33.31%、46.35%、47.65%、53.50%。根据干眼严重程度分为轻度干眼、中度干眼及重度干眼，它们的构成比依次为80.11%、19.03%、0.86%。

结论：干眼在研究人群中的患病率为40.37%，女性干眼患病率高于男性，且随年龄的增加干眼患病率呈上升趋势，高龄和女性是干眼的危险因素。

METHODS: A cross-sectional study was conducted on 6 027 residents aged 18-98 from 105 villages in Hotan, Xinjiang, China from January 2019 to September 2019. The subjective symptoms of dry eye were collected by ocular surface disease index(OSDI)questionnaire, and the objective signs were collected by testing fluorescein breakup time(FBUT)and Schirmer Ⅰ test, so as to analyze the prevalence and risk factors of dry eye.

RESULTS: A total of 6 339 subjects aged 18-98 years were recruited from residents in Hotan, Xinjiang, China. Relevant eye examinations and questionnaires were conducted on the subjects, of which 6 027 were valid questionnaires, with an effective recovery rate of 95.08%. The dry eye detection rate of 6 027 residents was 40.37%(2 433/6 027), and the dry eye detection rates of male and female were 36.47%(846/2 320)and 42.81%(1 587/3 707)respectively. The dry eye detection rates of 18-24 years old, 25-34 years old, 35-44 years old, 45-54 years old, 55-64 years old, and ≥65 years old were 13.77%, 15.67%, 33.31%, 46.35%, 47.65%, 53.50%, respectively. According to the severity of dry eye, they were divided into mild dry eye, moderate dry eye and severe dry eye, and their constituent ratios were 80.11%, 19.03% and 0.86%, respectively.

CONCLUSION: The prevalence of dry eye in the study population was 40.37%. The prevalence of dry eye in female was higher than that in male, and the prevalence of dry eye increased with the increase of age. Older age and female are the risk factors for dry eye.