Glaucoma is a leading cause of irreversible blindness in the world and its specific pathogenesis is not clear. More attention has been paid to intraocular pressure and aqueous outflow channel. In recent years, scholars began to attach more importance to the role of non-pressure dependent factors, such as corneal hysteresis(CH), in glaucoma. CH is a biomechanical parameter of cornea, which reflects the viscous resistance of cornea, i.e., the ability to absorb and disperse energy. CH can be easily acquired clinically and may serve as surrogate markers for biomechanical properties of tissues in the back of the eye, like the lamina cribrosa and peripapillary sclera, which may be related to the susceptibility of glaucomatous damage. Several studies have provided evidence of the associations between CH and clinically relevant outcomes in glaucoma. This article reviews the latest findings on CH and summarizes the measurement methods of CH, relations between CH and central corneal thickness, glaucomatous visual field progress, optic disc damage, retinal nerve fiber layer loss, etc.

黑龙江省自然科学基金项目(No.LH2020H041); 哈尔滨医科大学附属第一医院科研创新基金项目(No.2020M23)