目的：探讨白内障超声乳化联合人工晶状体植入术后囊袋收缩综合征(CCS)发生情况及其影响因素。

方法：回顾性研究。选取2018-09/2021-12期间于我院行白内障超声乳化联合人工晶状体植入术治疗的白内障患者1 987例1 987眼为研究对象，记录白内障患者术后CCS发生情况并根据术后是否发生CCS分为CCS组和无CCS组，比较两组患者术前的临床资料，使用多因素Logistic回归分析白内障超声乳化伴人工晶状体植入术后CCS的影响因素并构建预测模型。

结果：纳入患者1 987例1 987眼中术后发生CCS 38眼，术后CCS发生率为1.91%。CCS组中年龄≥65岁、糖尿病、青光眼、视网膜色素变性、葡萄膜炎、亲水性人工晶状体患者构成比显著高于无CCS组(均P<0.05)。经多因素Logistic逐步向前法回归分析显示年龄≥65岁、糖尿病、视网膜色素变性、葡萄膜炎、亲水性人工晶状体是影响白内障超声乳化联合人工晶状体植入术后CCS发生的危险因素(P<0.05)，在术后CCS危险因素的回归系数构建的预测模型的拟合优度好(P=0.421)。

结论：高龄、糖尿病、视网膜色素变性、葡萄膜炎以及人工晶状体材料性质是影响白内障超声乳化联合人工晶状体植入术后CCS发生的重要因素。

METHODS: A Retrospective study was conducted on the selected 1 987 patients(1 987 eyes)undergoing cataract phacoemulsification combined with intraocular lens implantation in the hospital between September 2018 and December 2021. According to the postoperative occurrence of CCS, they were divided into CCS group and non-CCS group. The clinical data in the two groups were compared. The influencing factors of CCS were analyzed by multivariate Logistic regression analysis. And the predictive model was constructed.

RESULTS: There were 38 eyes with postoperative CCS among the 1 987 cataract patients(1 987 eyes), with an incidence of 1.91%. The proportions of cases with age ≥65 years, diabetes mellitus, glaucoma, retinitis pigmentosa, uveitis and hydrophilic intraocular lens in CCS group were significantly higher than those in the non-CCS group(all P<0.05). Multivariate Logistic stepwise forward regression analysis showed that age ≥65 years, diabetes mellitus, retinitis pigmentosa, uveitis and hydrophilic intraocular lens were risk factors of CCS after phacoemulsification combined with intraocular lens implantation(P<0.05). The predictive model constructed based on regression coefficients of the risk factors had good goodness of fit(P=0.421).

CONCLUSION: Advanced age, diabetes mellitus, retinitis pigmentosa, uveitis and material properties of intraocular lens are important influencing factors of postoperative CCS.