目的：探讨角膜塑形镜矫治患者停戴时长对屈光状态、角膜内皮细胞的影响。

方法：选择2019-07/2020-07于本院配戴角膜塑形镜且近期拟停戴的青少年近视患者，根据球镜度数分为轻度组、重度组。于停戴时及停戴后1、2、3mo测定屈光状态、角膜形态、角膜内皮细胞、视觉质量等。

结果：停戴时两组角膜平K值、陡K值及平均K值低于戴镜前，停戴2mo恢复至戴镜前水平(P>0.05)。戴镜前与停戴后1、2、3mo比较两组角膜散光度数、表面规则指数、表面非对称指数均无显著差异(P>0.05)。与戴镜前相比，停戴后1、2、3mo两组角膜内皮细胞密度无变化(P>0.05)，两组停戴时六边形细胞比例低于戴镜前，停戴1mo恢复至戴镜前(P>0.05)。

结论：角膜塑形镜停戴3mo角膜形态及角膜内皮细胞可恢复至戴镜前水平。

METHODS: Adolescent myopia patients who wore orthokeratology lens from July 2019 to July 2020 and recently planned to stop wearing the lens were divided into mild group and severe group according to spherical equivalent. Refractive status, corneal morphology, corneal endothelial cells, and visual quality were measured at cessation and 1, 2 and 3mo after cessation.

RESULTS: The corneal flat K values, steep K values and mean K values in the two groups were lower at cessation than those before wearing lenses. These values returned to the level before wearing lenses at 2mo after cessation(P>0.05). The corneal astigmatism, surface regularity index and surface asymmetry index in each group showed no statistically significant difference before wearing lenses and at 1, 2 and 3mo after cessation(P>0.05). There was no significant change in corneal endothelial cell density of the two groups at 1, 2 and 3mo after cessation compared with those before wearing lenses(P>0.05). The proportion of hexagonal cells in the two groups was lower at cessation than that before wearing lenses, and it returned to the level before wearing lenses at 1mo after cessation(P>0.05).

CONCLUSION: Corneal morphology and corneal endothelial cells can be restored to the level before wearing orthokeratology lens at 3mo after cessation.