目的：分析1990年和2019年中国眼内异物发病和疾病负担情况。

方法：利用2019年全球疾病负担数据库，分析中国总人群、不同年龄组间1990年和2019年我国眼内异物发病和伤残调整寿命年(DALY)情况。

结果：2019年中国眼内异物发病例数为1 125.35万，发病率为79.12/10 000，2019年眼内异物发病数和发病率比1990年降低了12.87%和27.49%。 2019年中国眼内异物DALY为18.12万人年，2019年眼内异物DALY比1990年增加了6.14%。2019年发病例数、发病率和DALY最高的年龄组均为20～54岁年龄组，分别为801.26万、103.97/10 000和10.25万人年。1990～2019年中国眼内异物发病率呈降低趋势，平均年度变化百分比(AAPC)=-1.2%(95%CI： -1.8～-0.7，P<0.05)，DALY率也呈降低趋势，AAPC=-0.6%(95%CI： -2.1～0，P<0.05)。1990～2019年中国和全球眼内异物发病率和DALY率均呈下降趋势， 2019年，中国眼内异物发病率和DALY率明显高于全球及不同社会人口指数(SDI)地区。

结论：中国眼内异物发病率和DALY率虽然近年来呈降低趋势，但中国人口基数大，在全球范围内眼内异物负担占比仍然较大，应采取积极的预防措施以减轻眼内异物的疾病负担。

METHODS: Using the global burden of disease database in 2019, the incidence and disability adjusted life years(DALY)of foreign body in eyes in 1990 and 2019 of China were analyzed among the total population and different age groups of China.

RESULTS: In 2019, the number of cases of foreign body in eyes in China was 11.2535 million, and the incidence was 79.12/10 000. The number and incidence of foreign body in eyes in 2019 decreased 12.87% and 27.49% respectively compared with those in 1990. In 2019, the DALY of foreign body in eyes in China was 181 200 person-years, and the DALY of foreign body in eyes in 2019 increased by 6.14% compared with 1990. In 2019, the age groups with the highest number of cases, incidence and DALY were all 20-54 years old, which were 8 012 600, 103.97/10 000 and 102 500 person-years, respectively. From 1990 to 2019, the incidence of foreign body in eyes in China showed a decreasing trend, average annual percentage change(AAPC)=-1.2%(95%CI: -1.8～-0.7, P<0.05), and DALY rate also showed a decreasing trend, AAPC=-0.6%(95%CI:-2.1～0, P<0.05). From 1990 to 2019, the incidence and DALY rate of foreign body in eyes in China and the World showed a downward trend. In 2019, the incidence and DALY rate of foreign body in eyes in China were significantly higher than those in the World and regions with different sociodemographic index(SDI).

CONCLUSION: Although the incidence and DALY rates of foreign body in eyes in China have been decreasing in recent years, China has a large population base and the burden of foreign body in eyes is still large in the World. Active preventive measures should be taken to reduce the disease burden of foreign body in eyes.