[关键词]
[摘要]
蠕形螨是一种寄生于人体内的常见寄生虫,根据寄生的部位不同分为毛囊蠕形螨与皮脂蠕形螨。蠕形螨属于条件致病性微生物,部分感染者可无临床症状,但也可引起以睑缘炎为代表的多种常见的眼部疾病,其典型症状包括眼干涩、异物感、袖套样分泌物附着以及眼表刺激症状等。蠕形螨睑缘炎的诊断需根据临床表现及病原学检测共同确定,治疗方法包括植物精油在内多种药物及物理治疗。目前,对于蠕形螨睑缘炎的诊断及治疗方法日渐完善,但蠕形螨感染与其致病性之间的关系尚未明确。本文对目前蠕形螨的特点、蠕形螨睑缘炎的临床表现、诊断、治疗方法及存在的问题进行了总结,希望对未来蠕形螨的进一步研究提供参考依据。
[Key word]
[Abstract]
Demodex is one of the most common parasites in the human body. It can be classified into demodex folliculorum and demodex brevis based on the parasitic sites. It is an opportunistic pathogenic microorganism, and clinical symptoms may not appear in part of infected people, but the parasite can cause multiple common ocular diseases represented by blepharitis. Its typical symptoms include dry eyes, foreign body sensation in eyes, secretion attached to eyelashes, and ocular surface irritation. The diagnosis of demodex blepharitis should be based on the clinical manifestations and the results of etiological tests. The treatment is related to many kinds of drugs including plant essential oil and physical therapy. At present, diagnosing and treating demodex blepharitis is increasingly sophisticated, but the relationship between demodex infection and its pathogenicity remains unclear. This paper summarizes the current characteristics of demodex and the clinical manifestation, diagnosis, treatment, and existing issues of demodex blepharitis, hoping to provide a reference for future studies in demodex.
[中图分类号]
[基金项目]
国家自然科学基金资助项目(No.81800801)