目的：观察折叠式人工玻璃体球囊植入术在眼外伤和硅油依赖眼中的临床效果。方法：前瞻性病例研究。2017-10/2022-04在长沙市第一医院就诊的眼外伤和硅油依赖眼患者17例17眼，植入折叠式人工玻璃体球囊或者硅油取出术联合折叠式人工玻璃体球囊植入术。术后随访6mo，观察术前，术后1wk，6mo视力、眼压和眼轴情况，以及眼球结构及球囊情况。结果：术前残存视力患者6例，术后1wk，6mo视力与术前相比均无差异(P>0.05)。术前眼压偏低，术后1wk，6mo眼压与术前相比眼压升高。术后1wk，6mo眼轴长度没有变化。随访期内眼球外观及结构维持良好，球囊稳定，眼球没有萎缩。结论：折叠式人工玻璃体球囊植入术可保存眼球外观，阻止眼外伤后眼球萎缩，避免多次手术或摘除眼球，对眼外伤或硅油依赖眼有良好的应用价值。

AIM: To observe the clinical effect of foldable capsular vitreous body(FCVB)implantation on ocular trauma and silicone oil-dependent eyes.METHODS: A prospective case study was performed on 17 cases(17 eyes)with ocular trauma and silicone oil-dependent in the First Hospital of Changsha from October 2017 to April 2022. All patients underwent FCVB or silicone oil removal combined with FCVB implantation. The follow-up time was 6mo, and the visual acuity, intraocular pressure, ocular axes, normal external appearances and FVCB were observed at 1wk and 6mo after operation.RESULTS: Only 6 cases had visual acuity before operation, and there were no statistical differences in the visual acuity before and at 1wk and 6mo after operation(P>0.05). The intraocular pressure was low before operation, but it was elevated at 1wk and 6mo after operation. The axial length was unchanged at 1wk and 6mo after operation, and the appearance and structure of eyeball were well maintained, and FCVB was stable with no atrophy during the follow-up period.CONCLUSIONS: FCVB implantation can preserve the appearance of eyeball, and avoid atrophy of eyeball and repeated operation, which has favorable clinical application value in the treatment of ocular trauma and silicone oil-dependent eyes.

湖南省自然科学基金临床医疗技术创新引导项目(No.2020SK53010)