目的：观察小梁切除术治疗色素性青光眼的中远期临床效果。

方法：回顾性分析2010-01/2022-09于云南大学附属医院行小梁切除术治疗的色素性青光眼患者38例51眼的临床资料。术后随访3～144mo，分析纳入患者的眼压、视力及屈光状态，记录并发症情况，评估手术疗效。

结果：纳入患者术前平均使用降眼压药物种类2.90±0.12种，平均眼压18.89±7.40mmHg，术后3d，1、3、6mo，1a、末次随访时平均眼压分别为14.68±5.08、13.99±2.95、14.25±2.50、14.36±2.83、14.33±2.66、14.94±1.95mmHg，术后各时间点眼压均较术前明显降低(P<0.05)，术后各时间点眼压均无明显差异(P>0.05)。随访期间，纳入患者视力基本保持稳定，均无眼内炎、恶性青光眼发生。末次随访时，手术完全成功率为90%，部分成功率为8%，失败率为2%。

结论：小梁切除术治疗色素性青光眼可以解除反向瞳孔阻滞，有效控制眼压、稳定视力，是安全有效的治疗方法。

METHODS: The clinical data of 38 patients(51 eyes)who were diagnosed with PG and received trabeculectomy at the Affiliated Hospital of Yunnan University from January 2010 to September 2022 were retrospectively analyzed. The postoperative follow-up ranged from 3 to 144mo. The intraocular pressure(IOP), visual acuity and refractive status were analyzed, complications were recorded and surgical efficacy was evaluated.

RESULTS: The average preoperative use of IOP lowering drugs was 2.90±0.12, with a mean IOP of 18.89±7.40mmHg. The IOP at 3d, 1, 3, 6mo, 1a after surgery and the last follow-up visit were 14.68±5.08, 13.99±2.95, 14.25±2.50, 14.36±2.83, 14.33±2.66, 14.94±1.95mmHg, respectively, and postoperative IOP was significantly lower at all time points than that before surgery(P<0.05), while there was no significant difference at all time points after surgery(P>0.05). During the follow-up period, the visual acuity of all patients was stable, and no endophthalmitis or malignant glaucoma occurred. At the last follow-up, the complete success rate was 90%, the qualified success was 8%, and the failure rate was 2%.

CONCLUSION: Trabeculectomy is a safe and effective treatment method for PG, which can effectively control the IOP, and stabilize the visual acuity and relieve the reverse pupil block.