目的：探索全球针对葡萄膜炎的研究现状、研究热点及趋势，以期为葡萄膜炎领域相关研究者提供理论依据及参考，促进该领域的进一步发展。

方法：检索中国知网(CNKI)数据库、万方数据库及Web of Science核心合集数据库自建库至2023-08-24已发表的关于葡萄膜炎的相关文献，并通过GraphPad Prism 9、CiteSpace 6.2.R2与VOSviewer等软件对国家/发文机构、研究作者、高频关键词及爆点关键词等内容进行可视化分析。

结果：目前全球关于葡萄膜炎的相关研究已形成各个国家相应的科研团体，发文量位于前3位的国家分别为美国(7 585篇)、英国(2 412篇)及德国(1 679篇)； 国外发文量位于前3位的研究机构分别为哈佛大学、俄勒冈健康与科学大学及摩菲眼科医院，国内发文量位于前3位的研究机构分别为山东中医药大学附属眼科医院、重庆医科大学及中山大学中山眼科中心。中英文高频关键词和爆点关键词的分析结果显示，研究热点主要集中在针对葡萄膜炎发病机制和治疗方式的探讨等内容，针对葡萄膜炎治疗的相关研究热点向分子生物水平相关研究内容进行过渡，如分子生物信号通路(核因子κB信号通路，强度值为22.89)、生物制剂(阿达木单抗，强度值为32.21)及肿瘤坏死因子(强度值为48.44)等，相关研究也多向相关大鼠的基础实验进行扩展。

结论：全球葡萄膜炎的研究热点及趋势以精准诊断、发病机制及更佳有效的治疗手段为主，期待未来能够有更多学者致力于葡萄膜炎的研究，并取得新的突破和进展，通过大样本、多中心的临床研究提供高质量的研究证据。

METHODS: Relevant literatures on uveitis were retrieved from the China National Knowledge Infrastructure(CNKI)database, Wanfang database, and Web of Science core collection database since their establishment until 24 August 2023. The country/publishing institutions, research authors, high-frequency keywords, and burst keywords were visual analyzed by using software such as GraphPad Prism 9, CiteSpace 6.2. R2, and VOSviewer.

RESULTS: Research teams for uveitis have been formed in various countries globally. The top three countries in terms of publications are the United States of America(7 585 papers), the United Kingdom(2 412 papers)and Germany(1 679 papers). The top three foreign institutions in terms of publications are Harvard University, Oregon Health & Science University, and Moorfields Eye Hospital, while the top three domestic institutions are Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine, Chongqing Medical University, and Zhongshan Ophthalmic Center, Sun Yat-sen University. The analysis of high-frequency keywords and burst keywords in Chinese and English shows that research hotspots mainly focus on exploring pathogenesis and different treatment methods for uveitis. The research hotspots related to uveitis treatment are transitioning to molecular biology-related research topics, such as molecular biological signaling pathways(NF-κB signaling pathway with a strength value of 22.89), biological agents(adalimumab with a strength value of 32.21), and tumor necrosis factor(with a strength value of 48.44). Related research is also expanding to basic experiments on relevant rats.

CONCLUSIONS: In recent years, the research hotspots and trends of global uveitis mainly focus on precise diagnosis, pathogenesis, and more effective treatment methods. It is important for more scholars to dedicate themselves to uveitis-related research in the future to make breakthroughs and progress in the field. More large-scale and multicenter clinical studies on uveitis can provide high-quality research evidence.