目的：比较藏族与汉族年龄相关性白内障患者眼球生物学参数的差异，分析藏族患者眼球生物学参数的分布特征。

方法：回顾性队列研究。收集2019-01/2020-12就诊于我院的年龄相关性白内障患者661例1 030眼，其中藏族患者483例739眼，汉族患者178例291眼。术前所有患者均采用IOL Master 500测量眼轴长度、前房深度、角膜曲率、散光及散光轴向。

结果：藏族年龄相关性白内障患者眼轴长度为23.33(22.81，23.86)mm，前房深度为3.04(2.79，3.30)mm，散光度为0.73(0.47，1.07)D，平均角膜曲率为43.89±1.35 D，较汉族患者眼轴短，角膜曲率小(均P<0.05)。藏族患者的年龄与眼轴长度和前房深度均呈负相关，而与平均角膜曲率呈正相关(均P<0.05)。藏族患者中男性患者较女性患者眼轴更长、前房更深、角膜更平坦(均P<0.05)。

结论：藏族与汉族年龄相关性白内障患者的眼球生物学参数存在差异，不同年龄和性别藏族患者眼球生物学参数的分布有所变化。

METHODS:Retrospective cohort study. A total of 661 patients(1 030 eyes)with age-related cataract confirmed in the hospital between January 2019 and December 2020 were enrolled. The parameters of axial length, anterior chamber depth, keratometry, corneal astigmatism and astigmatic axis were measured by IOL Master 500 in 483 cases(739 eyes)of Tibetan age-related cataract patients and 178 cases(291 eyes)of Han patients.

RESULTS:The axial length, anterior chamber depth and corneal astigmatism of the Tibetan patients with age-related cataract were 23.33(22.81, 23.86)mm, 3.04(2.79, 3.30)mm and 0.73(0.47, 1.07)D. The mean keratometry was 43.89±1.35 D. The results indicated that Tibetan cataract patients had shorter axial lengths and smaller keratometry compared to Han patients(all P<0.05). Age in Tibetan patients was negatively correlated with axial length and anterior chamber depth, and positively correlated with keratometry(all P<0.05). Tibetan male patients had longer axial lengths, deeper anterior chambers, and flatter corneas compared to female patients(all P<0.05).

CONCLUSION:There were differences in ocular biometric parameters between age-related cataract patients of Tibetan and Han ethnicities. The distribution of ocular biometric parameters in Tibetan cataract patients varied across different age groups and gender groups.