目的：观察有晶状体眼后房型人工晶状体(ICL)植入术矫正中低度近视的临床效果。

方法：回顾性研究。纳入我院ICL植入术矫正的中低度近视患者48例85眼，观察术后1 a裸眼视力(LogMAR)、最佳矫正视力(LogMAR)、屈光状态、眼压、拱高与角膜内皮细胞计数等的变化情况。

结果：术后12 mo，患者裸眼视力-0.10(-0.20，-0.10)、有效性指数为1.07±0.13、最佳矫正视力-0.10(-0.20，-0.10)、安全性指数为1.10±0.14。实际矫正屈光度与预期矫正屈光度差值在±0.50 D范围占91%(77/85)，差值在±1.00 D范围占100%(85/85)。术后12 mo时拱高为501.16±210.46 μm。术前，术后6、12 mo的角膜内皮细胞密度比较无差异(F=1.050，P=0.352)。所有患者术后随访期间无前囊下混浊、白内障、瞳孔阻滞或其他威胁视力的并发症。

结论：ICL植入术矫正中低度近视具有良好的有效性、安全性与可预测性。

METHODS: Retrospective study. A total of 48 patients(85 eyes)with low to moderate myopia who underwent ICL implantation were included in the study. The changes in uncorrected visual acuity(LogMAR), corrected visual acuity(LogMAR), refractive outcomes, intraocular pressure, vault and endothelial cell were observed at 1 a postoperatively.

RESULTS: At 12 mo postoperatively, uncorrected and best-corrected visual acuity were -0.10(-0.20, -0.10)and -0.10(-0.20, -0.10), respectively, with an efficacy index of 1.07±0.13 and a safe index of 1.10±0.14. The difference between the actual corrected diopter and the expected corrected diopter was 91%(77/85)in the range of ±0.50 D, and 100%(85/85)in the range of ±1.00 D. The mean vault was 501.16±210.46 μm at 12 mo postoperatively. There was no significant difference in corneal endothelial cell density between preoperative and 6 and 12 mo postoperatively(F=1.050, P=0.352). All patients had no anterior subcapsular opacification, cataract, pupillary block, or other sight threatening complications during follow-up.

CONCLUSION: ICL implantation for the correction of low to moderate myopia has good efficacy, safety and predictability.