目的：探讨不同年龄组蠕形螨睑缘炎患者的临床特征及茶树油湿巾联合深度睑板腺按摩的疗效。

方法：回顾性收集2023-01/10就诊于空军军医大学西京医院眼科的蠕形螨睑缘炎患者146例292眼的病例资料，根据不同年龄将患者分为年龄≤45岁的A组(64例128眼)和年龄>45岁的B组(82例164眼)。分析两组治疗前，治疗后1、3 mo的双眼螨虫总计数、泪液分泌量、症状和体征评分及茶树油湿巾联合深度睑板腺按摩的疗效。

结果：治疗前A组螨虫计数7(6，8)只，少于B组8(7，9.25)只(P<0.05)。A组眼干评分6(6，7)分，低于B组11(10，12)分(P<0.001)。A组眼表刺激症状评分10(9，11)分，高于B组6(6，7)分(P<0.001)。治疗1 mo后，两组患者螨虫计数下降，症状与体征评分均降低，坚持治疗3 mo各临床指标仍有不同程度改善，其中B组患者在治疗持续至3 mo时，螨虫计数仍有减少\〖-1(-3，0)只\〗。

结论：年龄大于45岁的年长患者螨虫数量高于45岁以下患者，眼干严重，但眼表刺激症状较轻。茶树油湿巾联合深度睑板腺按摩治疗蠕形螨睑缘炎能有效减少不同年龄患者的螨虫数量，但泪液分泌量治疗后无明显变化，较长的治疗周期可获得持续的临床获益。

METHODS:The clinical data of 146 patients(292 eyes)diagnosed with demodex blepharitis, hospitalized in Department of Ophthalmology, Xijing Hospital from January 2023 to October 2023, was collected in this retrospective study, and the patients were divided into group A(64 cases with 128 eyes)aged ≤45 years old and group B(82 cases with 164 eyes)aged >45 years old according to different ages. The differences in total numbers of binocular mites, Schirmer I tests, symptom and sign scores before, and at 1 and 3 mo after the treatment of the tea tree oil wipes combined with deep massages of the meibomian glands were analyzed between the two groups.

RESULTS: Before the treatments, the total number of the mites in the group A \〖7(6, 8)\〗 was lower than that in the group B \〖8(7, 9.25); P<0.05\〗. The dry eye score in the group A \〖6(6, 7)\〗 was lower than that in the group B \〖11(10, 12); P<0.001\〗, and the ocular surface irritation symptom score in the group A \〖10(9, 11)\〗 was higher than that in the group B \〖6(6, 7); P<0.001\〗. Both groups experienced a decrease in mite counts and improvement in symptoms and signs scores at 1 mo after treatment, and there was still a degree of improvement in all clinical indicators, with patients in the group B showing a further reduction in mite counts \〖-1(-3, 0)\〗 even after the treatment was continued for 3 mo.

CONCLUSION:The total numbers of mites in patients of older than 45 years old were higher than those in patients of ages younger than 45, and older patients have more serious dry eyes, with less serious symptoms of ocular surface irritation. The treatment can effectively reduce the number of mites in patients of different ages with demodex blepharitis, but the outcomes of Schirmer I tests do not change after the treatment. Longer treatment duration provide sustained clinical benefits.