Making stereopsis related to the ability of ocular deviation: a new paradigm for assessment of intermittent exotropia
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Xin-Ping Yu and Rui-Xin Wang. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510623, Guangdong Province, China. yuxp@mail.sysu.edu.cn; ruiruiw413@aliyun.com

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Supported by the National Natural Science Foundation of China (No.82070995; No.82301256); Youth S&T Talent Support Programme of Guangdong Provincial Association for Science and Technology.

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    Abstract:

    AIM: To investigate the underlying factors by establishing a new paradigm for assessing control ability under stereopsis testing conditions. METHODS: This was a prospective observational study. We evaluated the control ability of intermittent exotropia (IXT) patients in three conditions: natural 2D optotype viewing, 2D optotype viewing with polarized glasses, and 3D optotype viewing with polarized glasses. Recording with a smartphone, we captured videos to analyze the accurate time of spontaneous exodeviation and subsequent realignment before and after breaking fusion. Additionally, the correlation of stereopsis were also analyzed. RESULTS: A total of 48 patients (age range: 4-33y; 54.17% male) participated in the study. When viewing 3D optotypes with polarized glasses, their median control scores were 1 (interquartile range, 0-4) at distance and 0 (0-1) at near. These scores were significantly better than those observed under natural viewing conditions, which were 2.5 (1-5) at a distance and 1 (0-3) at near (Friedman test, P=0.049). Furthermore, those subjects who exhibited exophoria (realignment within 2 seconds) while viewing 3D optotypes with polarized glasses were more likely to have measurable stereo vision (Kendall’s τb=-0.344, P=0.018). CONCLUSION: IXT patients exhibit enhanced control ability when using polarized glasses to view 3D optotypes, notably improving realignment capabilities. This expands our understanding of current tests and offers a potentially sensitive method for assessing IXT severity.

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Jian-Bing Li, Wan-Ting Kong, Tao Shen, et al. Making stereopsis related to the ability of ocular deviation: a new paradigm for assessment of intermittent exotropia. Int J Ophthalmol, 2025,(2):308-314

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Publication History
  • Received:February 21,2024
  • Revised:August 23,2024
  • Adopted:
  • Online: January 16,2025
  • Published: